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Multi-Omics · Microbiomics

Precision Begins at
the Microbiome

16S Sequencing · Metagenomics · Microbial Diversity · Clinical Translation · Gut-Immune Axis · Dysbiosis Profiling

38T+

Microbial Cells

1,000+

Resident Species

100%

Patient-Centered

Board

Certified Standard

Department Overview

Mi·cro·bi·o·mics

/ ˌmīkrōbīˈōmiks /  ·  noun

noun  ·  precision science

The comprehensive study of the microbiome - the collective genomes, diversity, and functional activity of all microbial communities inhabiting the human body and their profound influence on immunity, metabolism, neurology, and disease.

Origin

From Greek mikros (small) + Latin bios (life) + Greek -ome (complete set). The term microbiome was introduced by Joshua Lederberg in 2001 to describe the totality of microorganisms sharing the human body recognizing them as an essential component of human biology rather than passive inhabitants.

The Microbiomics Department at the American Board of Precision Medicine trains clinicians to understand the human microbiome as an active and modifiable determinant of health equipping physicians to interpret microbial diversity data, identify dysbiotic signatures, and apply microbiome science to the prevention, diagnosis, and treatment of complex disease.

From 16S rRNA sequencing and shotgun metagenomics to functional pathway analysis and gut-immune axis profiling, this department bridges the frontier of microbial science and clinical medicine - teaching physicians how microbial communities influence drug metabolism, immune regulation, mental health, and the trajectory of chronic disease.

With trillions of microbial cells outnumbering human cells and encoding a genetic repertoire 150 times larger than the human genome, the microbiome is not a bystander - it is a co-author of human health, and at ABOPM, its mastery is treated as an indispensable pillar of precision care.

38T+

Microbial Cells

1,000+

Resident Species

Clinical Possibilities

Microbiomics Department · ABOPM

Where the Microbiome Meets
Clinical Purpose

The Microbiomics Department at ABOPM exists at the intersection of microbial ecology and patient care - training physicians to decode the microbiome, apply its insights, and transform outcomes across every clinical specialty.

Microbiomic Discovery

Advancing research in metagenomic sequencing, microbiome composition and diversity analysis, host–microbe interaction, and microbial metabolite signaling deepening our understanding of how the human microbiome shapes immunity, metabolism, and disease susceptibility.

Clinical Translation

Bridging microbiome laboratory science and bedside medicine developing board-certified frameworks for dysbiosis assessment, microbiome-informed therapeutics, and precision interventions across gastroenterology, immunology, psychiatry, and oncology.

Physician Education

Building the next generation of microbiomics-fluent clinicians through rigorous board standards, interdisciplinary training, and collaboration across gastroenterology, infectious disease, immunology, and integrative medicine.

"The microbiome is not a bystander - it is a participant in every aspect of human health. The Microbiomics Department at ABOPM trains physicians to engage that participant, interpret its signals, and harness its potential for precision care."

American Board of Precision Medicine · Microbiomics Department
Microbiomics Department · ABOPM

Translating the Microbiome
Into Clinical Impact

The microbiome is the most populous and ecologically complex dimension of human biology - trillions of microorganisms that actively shape immunity, metabolism, and neurological function. Learning to read it is not optional for the future of medicine - it is foundational.

Microbiomics equips clinicians to move beyond host-centric medicine and into the microbial ecosystem that governs health from within - enabling earlier detection of dysbiosis, targeted restoration of microbial balance, and care that accounts for the full biological community living inside every patient.

Firmicutes ~45% Bacteroidetes ~40% Proteobacteria ~5% Actinobacteria ~3% Verrucomicrobia ~2% Fusobacteria ~1% Gut Microbiome 16S rRNA Sequencing Shotgun Metagenomics Dysbiosis Index FMT / Probiotics

By mastering microbiomics, clinicians gain the power to:

01
Detect Dysbiosis Early
Identify microbial imbalances and loss of diversity before systemic disease emerges - using metagenomic signatures as early warning indicators across gastrointestinal, metabolic, and immune conditions.
02
Personalize Treatment
Apply microbiome profiling to tailor dietary interventions, probiotic regimens, prebiotic strategies, and fecal microbiota transplantation - matching therapy to each patient's unique microbial ecosystem.
03
Interpret the Gut-Brain-Immune Axis
Leverage microbiomic data to understand bidirectional signaling between the gut microbiome, the immune system, and the central nervous system - connecting microbial ecology to psychiatric, neurological, and autoimmune disease.
04
Anticipate Disease Risk
Use microbiome diversity indices and keystone species signatures to stratify patients for colorectal cancer, metabolic syndrome, inflammatory bowel disease, and beyond enabling preventive action before symptoms arise.
05
Lead Precision Care
Become the microbiomics-fluent clinician your institution needs - positioned at the frontier of medicine where microbial ecology meets measurable, transformative patient impact.

Why Microbiomics Fluency Is Non-Negotiable

The microbiome is active. The clinical tools are ready. The question is, are you?

Patient Outcomes

Microbiome-guided care improves treatment response in IBD, metabolic disease, and oncology immunotherapy and opens new preventive pathways unavailable through host genetics alone.

Future-Ready Practice

Microbiome-based diagnostics and therapeutics are entering mainstream clinical pipelines across gastroenterology, oncology, and psychiatry - clinicians who can't interpret microbiome data will fall behind.

Clinical Authority

Board certification in microbiomics establishes you as a precision medicine leader in one of the fastest-growing fields in biomedicine where clinical expertise is urgently needed and rarely held.

Interdisciplinary Impact

Microbiomics connects every specialty: gastroenterology, psychiatry, immunology, oncology, and infectious disease giving you tools to address disease at the interface of host and microbe across all of medicine.

Active research areas driving microbiomic medicine forward:

01
Metagenomic Sequencing
Applying shotgun metagenomics and 16S rRNA sequencing to characterize the full microbial community identifying species composition, functional gene content, and strain-level diversity across gut, oral, skin, and other body-site microbiomes.
02
Host–Microbe Interaction
Investigating how microbial metabolites, lipopolysaccharides, and short-chain fatty acids signal to host immune, endocrine, and nervous systems uncovering the molecular mechanisms by which the microbiome governs systemic health.
03
Dysbiosis & Disease Association
Identifying microbial signatures linked to IBD, colorectal cancer, type 2 diabetes, depression, Parkinson's disease, and autoimmunity establishing causal and correlative relationships between microbiome composition and clinical outcomes.
04
Microbiome-Based Therapeutics
Advancing fecal microbiota transplantation (FMT), precision probiotics, synbiotics, and phage therapy developing microbiome-targeted interventions with defined mechanisms and evidence-based clinical indications.
05
Microbiome & Immunotherapy Response
Exploring how gut microbiome composition predicts and modulates response to checkpoint inhibitors, CAR-T therapy, and cancer vaccines positioning the microbiome as a critical determinant of oncologic treatment outcomes.
Microbiomics Research · ABOPM
Pushing the Frontier of Microbiomic Science

The microbiomics revolution is not a future event - it is happening now. Metagenomic profiling, microbiome-based therapeutics, and host–microbe interaction mapping are actively reshaping how disease is prevented, treated, and monitored at the microbial ecosystem level.

The ABOPM Microbiomics Department positions clinicians at the center of this transformation equipping them with the scientific literacy, clinical frameworks, and board-certified credentials to lead microbiomic medicine in any specialty.

$3.1B
Global microbiome therapeutics market by 2028
38T
Microbial cells in the human body
90%
of serotonin produced in the gut
Explore Blog Topics Read clinical insights, case studies & microbiomics updates on our blog
Microbiomics Department · ABOPM

Meet Our Leadership

Director of Microbiomics

Alex Mohr, PhD — Director of Microbiomics
Director
Microbiomics
Director of Microbiomics

Alex Mohr, PhD

Microbiome Scientist · Multi-Omics & Systems Biology · Precision Medicine & Gut Health Research
Microbiome scientist advancing precision medicine through multi-omics and gut health research bridging microbial ecology and clinical application to improve human health outcomes.

Dr. Mohr is Director of Microbiomics at Theriome, where he leads initiatives that integrate multi-omics and systems biology to advance precision medicine. As a co-founder of Theriome, he has helped pioneer research on the gut microbiome and its role in human health and disease.

His work uses bioinformatics and multi-omic analyses to clarify the relationships among microbiota, host metabolism, and health outcomes. He emphasizes microbiome-based interventions that can improve resilience and inform therapeutic strategies across a range of clinical conditions.

Dr. Mohr's research integrates metagenomic, metabolomic, and proteomic datasets to build a comprehensive understanding of host–microbe interactions translating systems-level findings into actionable precision medicine tools for clinicians and patients.

Dir.
Microbiomics · Theriome
Co-
Founder · Theriome
PhD
Multi-Omics Research
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Faculty Members

Our faculty roster is growing - announcements coming soon.

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Faculty position open

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Genomics Department · ABOPM

Shaping the Future
of Precision Medicine

As precision medicine continues to evolve, genomics will play an increasingly central role in redefining how disease is understood, predicted, and treated at the molecular level.

The Genomics Department at ABOPM remains committed to advancing this field through scientific leadership, clinical innovation, and collaborative discovery. Together with our global community of physicians and researchers, we are helping shape the future of next-generation healthcare.

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