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Multi-Omics · Genomics

Precision Begins at
the Genome

Sequencing · Pharmacogenomics · Variant Interpretation · Clinical Translation · Epigenetics · Hereditary Risk

3B+

Base Pairs

20K+

Clinical Genes

100%

Patient-Centered

Board

Certified Standard

Department Overview

Ge·nom·ics

/ jəˈnōmiks /  ·  noun

noun  ·  precision science

The branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes and the clinical application of that knowledge to human health.

Origin

From Greek genesis (origin) + -ome (complete set). First used in 1986 by scientist Tom Roderick to describe the science of mapping entire genetic sequences.

The Genomics Department at the American Board of Precision Medicine translates the science of the human genome into actionable clinical knowledge - equipping physicians to interpret genetic data, identify hereditary risk, and personalize care at the molecular level.

From whole-genome sequencing and variant interpretation to pharmacogenomics and hereditary cancer risk, this department bridges the gap between laboratory discovery and bedside practice - training clinicians in the tools that define the future of medicine.

Grounded in rigorous board standards and driven by an interdisciplinary framework, genomics at ABOPM is not a subspecialty - it is the foundation of precision care.

3B+

Base Pairs Mapped

20K+

Protein-Coding Genes

Clinical Possibilities

Genomics Department · ABOPM

Where the Genome Meets
Clinical Purpose

The Genomics Department at ABOPM exists at the intersection of molecular science and patient care — training physicians to decode the genome, apply its insights, and transform outcomes across every clinical specialty.

Genomic Discovery

Advancing research in whole-genome sequencing, variant pathogenicity, and epigenomic profiling — expanding our understanding of the genetic architecture of human disease.

Clinical Translation

Bridging the gap between laboratory genomics and bedside medicine — developing board-certified frameworks for pharmacogenomics, hereditary risk, and precision therapeutics.

Physician Education

Building the next generation of genomics-fluent clinicians through rigorous board standards, interdisciplinary training, and collaboration across medicine and molecular science.

"The genome is not destiny — it is a map. The Genomics Department at ABOPM trains physicians to read it, interpret it, and act on it with precision and purpose."

— American Board of Precision Medicine · Genomics Department
Genomics Department · ABOPM

Translating the Genome
Into Clinical Impact

The genome is the most complete biological map of a human being ever assembled. Learning to read it is not optional for the future of medicine — it is foundational.

Genomics equips clinicians to move beyond symptom management and into the molecular root causes of disease — enabling earlier detection, more precise therapeutics, and care that is truly individualized at the DNA level.

A T G C T A C G SNP BRCA1 VUS GWAS

By mastering genomics, clinicians gain the power to:

01
Detect Disease Earlier
Identify genetic variants and hereditary risk factors before symptoms emerge, enabling preventive intervention at the earliest possible stage.
02
Personalize Treatment
Apply pharmacogenomics to prescribe the right drug at the right dose for each patient's unique genetic profile eliminating costly trial-and-error.
03
Interpret Variants
Classify pathogenic variants from whole-genome sequencing with clinical confidence, translating raw data into actionable patient decisions.
04
Anticipate Risk
Use polygenic risk scores and hereditary panels to stratify patients and design individualized prevention strategies before disease develops.
05
Lead Precision Care
Become the genomics-literate clinician your institution needs positioned at the frontier of medicine where genomic science meets patient impact.

Why Genomics Fluency Is Non-Negotiable

The science is here. The clinical tools are ready. The question is, are you?

Patient Outcomes

Genomics-guided care demonstrably improves survival rates, reduces adverse drug reactions, and enables true preventive medicine.

Future-Ready Practice

Genome sequencing costs have dropped 99.9%. Genomic data is now routinely generated, clinicians who can't interpret it will be left behind.

Clinical Authority

Board certification in genomics establishes you as a recognized leader, differentiating your expertise in an era where precision medicine is standard of care.

Interdisciplinary Impact

Genomics connects every specialty: oncology, cardiology, neurology, reproductive medicine - giving you tools that transcend clinical silos.

Active research areas driving genomic medicine forward:

01
Whole Genome Sequencing
Decoding the complete 3-billion base pair genome to uncover rare variants, structural mutations, and novel disease associations invisible to targeted panels.
02
Pharmacogenomics
Mapping how genetic variants alter drug metabolism, efficacy, and toxicity - enabling dose optimization and adverse event prevention across every prescription.
03
Hereditary Cancer Risk
Identifying pathogenic variants in genes like BRCA1/2, PALB2, MLH1, and Lynch syndrome loci to guide surveillance, prophylactic intervention, and family counseling.
04
Polygenic Risk Scores
Aggregating thousands of common variants into predictive risk models for complex diseases - enabling population-scale precision prevention strategies.
05
Epigenomics & Gene Expression
Studying how methylation, chromatin structure, and regulatory elements control gene expression - bridging the gap between genetic sequence and biological phenotype.
Genomics Research · ABOPM
Pushing the Frontier of Genomic Science

The genomic revolution is not a future event - it is happening now. Whole genome sequencing, pharmacogenomics, and polygenic risk modeling are actively reshaping how disease is detected, treated, and prevented at the molecular level.

The ABOPM Genomics Department positions clinicians at the center of this transformation - equipping them with the scientific literacy, clinical frameworks, and board-certified credentials to lead genomic medicine in any specialty.

$10B
Annual genomics research funding globally
500+
FDA-approved pharmacogenomic drug labels
72%
of oncologists now use genomic profiling
Explore Blog Topics Read clinical insights, case studies & genomics updates on our blog
Genomics Department · ABOPM

Meet Our Leadership

— Director of Genomics —

Puya Yazdi, MD — Director of Genomics
Director
Genomics
Director of Genomics

Puya Yazdi, MD

Physician-Scientist · Genomics, Bioinformatics & AI-Driven Precision Medicine
Pioneering the translation of advanced genomic science into scalable, AI-driven healthcare solutions worldwide.

Dr. Yazdi completed his medical training at USC and residency at Stanford University, later becoming a Clinical Fellow in regenerative medicine at UC Irvine. His clinical foundation spans the intersection of genomics, bioinformatics, and artificial intelligence.

As founder of Systomic Health and a leader at SelfDecode, he has pioneered genomic technologies adopted by biotechnology companies and global health platforms — driving a new era of personalized, precision medicine.

MD
USC · Stanford
Fellow
Regen. Med. · UCI
2x
Founder · Systomic
Connect on LinkedIn
Department Directors
Tyler Panzner, PhD — Director of Functional Genomics & Pharmacology
Director
Functional Genomics & Pharmacology
Director of Functional Genomics & Pharmacology

Tyler Panzner, PhD

Molecular & Cellular Pharmacologist · Genomic Health Specialist
Pharmacologist focused on nutraceutical safety, genetic personalization, and pharmacological rigor.

Dr. Panzner earned a BS in Cellular & Molecular Biology from the University of South Florida and a PhD in Molecular & Cellular Pharmacology from Stony Brook University. His doctoral research focused on extracellular vesicles and their role in breast cancer metastasis and tumor-immune crosstalk.

After analyzing his own genome and resolving chronic health issues through targeted nutrition and lifestyle changes, he founded Holistic Genetic Health Solutions. His educational platform on safe supplementation reaches over 3 million monthly viewers across social media.

3M+
Monthly Viewers
PhD
Stony Brook Univ.
BS
Univ. South Florida
Connect on LinkedIn
Gregory Nacarelli, ND, PhD, MS, CNS — Director of Nutrigenomics
Director
Nutrigenomics
Director of Nutrigenomics

Gregory Nacarelli, ND, PhD

Precision Health Educator & Consultant · MS, CNS · Multiomics & Integrative Medicine
Precision health educator and consultant focused on integrating multiomics into clinical practice.

Dr. Nacarelli earned his Doctor of Naturopathic Medicine from Bastyr University, a Master's in individualized genomics & health from Johns Hopkins University, and a PhD in healthcare genetics & genomics from Clemson University. His dissertation focused on nutrigenomics, metabolomics, and cardiovascular disease.

He works as a precision health consultant with Theriome and SelfDecode, seeing clients for precision health consults while educating practitioners on applying precision health and nutrigenomics in clinical care.

ND
Bastyr University
PhD
Clemson Univ.
MS
Johns Hopkins
Connect on LinkedIn

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Genomics Department · ABOPM

Shaping the Future
of Precision Medicine

As precision medicine continues to evolve, genomics will play an increasingly central role in redefining how disease is understood, predicted, and treated at the molecular level.

The Genomics Department at ABOPM remains committed to advancing this field through scientific leadership, clinical innovation, and collaborative discovery. Together with our global community of physicians and researchers, we are helping shape the future of next-generation healthcare.

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Precision Medicine

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The Rise of Precision Oncology: How Genomics Is Transforming Cancer Care

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Advancing education, certification, and leadership to shape a genomics-driven, data-intelligent future of healthcare.

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